Laser Therapy/ Photobiomodultion

Low-level laser irradiation induces in vitro proliferation of mesenchymal stem cells

Summary:

To evaluate the effect of low-level laser irradiation on the proliferation and possible nuclear morphological changes of mouse mesenchymal stem cells.

Conclusion:

Low-level laser irradiation stimulated the proliferation of mouse mesenchymal stem cells without causing nuclear alterations. The biostimulation of mesenchymal stem cells using laser therapy might be an important tool for regenerative therapy and tissue engineering.

Author & Journal:Augusto Galv√£o Barboza,Carlos, et al, eintstein, 2014

Preliminary clinical experience of low-level laser therapy for the treatment of canine osteoarthritis-associated pain: A retrospective investigation on 17 dogs

Summary:

Laser therapy (aka photobiomodulation) is often used to treat OA in veterinary patients, but the evidence to support this treatment is weak. At the time of this publication, there was one single prior publication investigating laser therapy for dogs with elbow OA (Looney et. al, Can Vet J 2018). This study found that with the laser and protocol studied (980 nm, 5-12 W, CW, 1-2.4W/cm2, 10-19 J/cm2, non-contact mode, scanning method; treatment 2x week for 3 weeks then once a week for 3 weeks), laser-treated dogs (n=11) showed significantly (p=0.001) greater reduction in lameness compared to sham (n=9) treated dogs. NSAID dose was also able to be decreased in 9 of the 11 laser-treated dogs. The authors of the current study (Barale et. al) aimed to report the clinical outcomes following a different laser therapy protocol in dogs with OA.

Conclusion:

This retrospective report provides a basis for future investigations, needed to clarify whether laser therapy may be beneficial to treat canine OA-associated pain. The preliminary findings are promising and suggest that LLLT may help to reduce the analgesic administration and improving client satisfaction and the quality of life of dogs with OA.

Author & Journal:Loris Barale, Paolo Monticelli, Massimo Raviola, and Chiara Adami, Open Vet J., April 2020