References

Determining the optimal age for gonadectomy of dogs and cats.

Summary:

Elective gonadectomy of dogs and cats is one of the most common veterinary procedures in the United States. Increasingly, dog owners and members of the veterinary profession throughout the world have questioned the optimal age for performance of these procedures and whether these procedure should even be performed as elective surgeries.

Author & Journal:Kustritz MVR, JAVMA 231(11): 1665-1675, 2007

Developmental orthopedic disease

Summary:

Developmental orthopedic diseases are a common cause of pain and lameness in young dogs. Most occur in large-breed dogs with rapid growth rates.

Conclusion:

This article reviews the signalment, etiology and pathogenesis, clinical signs, diagnosis, treatment, and prognosis for many of the common developmental orthopedic diseases, including hypertrophic osteodystrophy, panosteitis, osteochondrosis, Legg-Calve-Perthes disease, hip dysplasia, elbow dysplasia, and pes verus.

Author & Journal:Demko J, et al, Vet Clin Small Anim 2005 35:1111-1135

Diagnostic imaging of canine elbow dysplasia: a review.

Summary:

Canine elbow dysplasia (CED) is a common developmental disorder of the cubital joint of dogs. CED is comprised of fragmented medial coronoid process (FMCP), ununited anconeal process (UAP), osteochondrosis (OC), and elbow incongruity. Multiple imaging modalities have been used to assess this complex of disorders and the severity of the pathologic changes. Radiography has been used as a surveying tool for assessment of CED for many years. Recently, alternate techniques and modalities have expanded our knowledge of CED and our clinical approach to this disorder. Nuclear medicine has been used to aid in localizing lameness to the elbow joint. Ultrasonography has proven helpful for imaging the soft tissue structures adjacent to the joint as well as superficial bone abnormalities, including visualization of FMCP. Computed tomography and magnetic resonance imaging are advanced imaging modalities that allow visualization of the elbow in multiple planes and into three-dimensional reconstructions, thus allowing lesions to be more accurately and comprehensively visualized. Assessment of elbow incongruity in particular has been benefitted by these advanced imaging techniques because of the importance of sagittal and dorsal plane imaging and reconstructions for accurately determining the relationships between radial and ulnar articular surfaces.

Conclusion:

Comparative studies using multiple techniques and imaging modalities with correlation to reference standards and patient outcomes will be vital to continued progress in this area.

Author & Journal:Cook CR, et al, Vet Surg 2009 38:144-153

Diagnostic value of intra-articular anaesthetic in primary osteoarthritis of the hip.

Summary:

“We investigated 42 patients who were being considered for primary total hip arthroplasty (THA), but in whom it was uncertain whether the hip was the source of their pain.”

Conclusion:

“Of 33 patients who gained pain relief from their injection, 32 subsequently had successful THA. The remaining patient has not had surgery.”

Author & Journal:Crawford, R.W., et al, The Journal of Bone and Joint Surgery, 1998

Double pelvic osteotomy for the treatment of hip dysplasia in young dogs.

Summary:

The aim of this study was to evaluate the feasibility of the double pelvic osteotomy (DPO) (osteotomy of the ilium and pubis) to treat clinical cases of hip dyplasia in young dogs instead of performing a triple pelvic osteotomy (TPO) (osteotomy of the ilium, pubis, and ischium).

Conclusion:

Restoration of normal joint congruity (PC from 50 to 72%) and maintenance of the pelvic geometry without pelvic narrowing were the most intriguing features of DPO. The complications observed were greatly reduced when using dedicated DPO plates. Based on our experience, the morbidity after unilateral and bilateral DPO was lower than after TPO because elimination of the ischiatic osteotomy allowed for increased stability of the pelvis. The surgical technique of DPO was a little more demanding than TPO because of the difficulty in handling and rotating the acetabular iliac segment, but this difficulty was offset by elimination of ischial osteotomy.

Author & Journal:Vezzoni A, et al, VCOT 2010

Double-blind evaluation of implants of gold wire at acupuncture points in the dog as a treatment for osteoarthritis induced by hip dysplasia.

Summary:

Thirty-eight dogs with hip dysplasia were studied to evaluate the use of gold wire implants at acupuncture points around the hip joints.

Conclusion:

Radiographs were taken at the beginning and end of the study. Although the data collected from both groups by the veterinarians and the owners showed a significant improvement of locomotion and reduction in signs of pain (P=0.036 for the veterinary evaluation and locomotion and P=0.0001 and P=0.0034 for the owners’ evaluation of locomotion and pain, respectively), there were no statistically significant differences between the treated and control groups (P=0.19 and P=0.41, P=0.24, respectively).

Author & Journal:Hielm-Bjorkman A, et al, Vet Rec 149(15):452-456, 2001

Early clinical experience with osteochondral autograft transfer for treatment of osteochondritis dissecans of the medial humeral condyle in dogs.

Summary:

To establish whether osteochondral autograft transfer (OAT) procedures for osteochondritis dissecans (OCD) of the canine elbow would restore articular contour, resurface osteochondral defects with hyaline cartilage, and resolve lameness in the short term.

Conclusion:

OAT procedures are technically feasible in the canine elbow. In elbows with concurrent MCD, proximal ulnar osteotomy may improve likelihood of positive clinical outcome.

Author & Journal:Fitzpatrick N, et al, Vet Surg 2009 38:246-260

Effect of acupuncture on pain and quality of life in canine neurological and musculoskeletal diseases.

Summary:

This prospective study investigated the effects of acupuncture alone or combined with analgesics in chronic pain and quality of lifeassessed by owners for up to 24 weeks in 181 dogs with neurological and musculoskeletal diseases. The scores before and after the onset of treatment were evaluated using the Wilcoxon test and the evolution of success was evaluated by Kaplan-Meier curves. Differences were considered significant at P < 0.05.

Conclusion:

The success rates for Helsinki chronic pain index (HCPI), quality of life assessment, and visual analog scales (VAS) for pain and locomotion were 79%, 84%, 78%, and 78% of the animals, respectively, when both diseases and groups of treatment were combined. Dogs with musculoskeletal disorders had greater improvement in HCPI (P = 0.003) and VAS locomotion (P = 0.045) than those with neurological disorders. Use of acupuncture alone or in combination with analgesics reduced pain and improved quality of life in dogs with neurological and musculoskeletal diseases.

Author & Journal:Silva NE, et al, Can Vet J 58(9):941-951, 2017

Effect of adipose-derived mesenchymal stem and regenerative cells on lameness in dogs with chronic osteoarthritis of the coxofemoral joints: a randomized, double-blinded, multicenter, controlled trial.

Summary:

Autologous stem cell therapy in the field of regenerative veterinary medicine involves harvesting tissue, such as fat, from the patient, isolating the stem and regenerative cells, and administering the cells back to the patient. Autologous adipose-derived stem cell therapy has been commercially available since 2003, and the current study evaluated such therapy in dogs with chronic osteoarthritis of the hip.

Conclusion:

Dogs treated with adipose-derived stem cell therapy had significantly improved scores for lameness and the compiled scores for lameness, pain, and range of motion compared with control dogs. This is the first randomized, blinded, placebo-controlled clinical trial reporting on the effectiveness of stem cell therapy in dogs.

Author & Journal:Black LL, et al, Vet Therapeutics 2007

Effect of age at gonadectomy on the probability of dogs becoming overweight.

Summary:

To determine whether gonadectomy or age at gonadectomy was associated with the risk that dogs would subsequently become overweight.

Conclusion:

Gonadectomized dogs had a greater risk of being overweight than did sexually intact dogs, but this risk was not influenced by age at gonadectomy. Opportunities exist for veterinarians to provide counseling during the first years after gonadectomy to help dogs maintain a healthy weight.

Author & Journal:Lefebvre SL, et al, J Am Vet Med Assoc 2013; 243:236-243