Summary: To determine the effects of an omega-3 fatty acid and protein-enriched diet, physical rehabilitation, or both on radiographicfindings and markers of synovial inflammation in dogs following tibial plateau leveling osteotomy and arthroscopic surgery for treatment of cranial cruciate ligament disease. DESIGN Randomized, prospective clinical trial. ANIMALS 48 dogs with unilateral cranial cruciate ligament disease.
Conclusion: Results suggested that feeding the TF can result in lower synovial fluid PGE2 concentrations and that both the TF and rehabilitation can reduce progression of osteoarthritis in the 6 months following tibial plateau leveling osteotomy; clinical relevance of slower osteotomy healing in dogs fed the TF was unclear.
Author & Journal:Verpaalen VD, et al, J Am Vet Med Assoc 252:701-709, 2018