Nutrition

Inhibition of cyclooxygenase-2 expression and prostaglandin E2 production in chondrocytes by avocado soybean unsaponifiables and epigallocatechin gallate

Summary:

“To evaluate the anti-inflammatory effect of the combination of avocado soybean unsaponifiables (ASU) and epigallocatechin gal- late (EGCG) on cyclooxygenase-2 (COX-2) expression and prostaglandin E2 (PGE2) production in cytokine-activated equine chondrocytes.”

Conclusion:

“The present study demonstrates that the anti-inflammatory activity of ASU and EGCG is potentiated when used in combination. This combination may offer an attractive supplement or alternative to non-steroidal anti-inflammatory drugs (NSAIDs) in the management of osteoarthritis.”

Author & Journal:Heineckey, L.F., et al, Osteoarthritis and Cartilage, 2010

Canine Hip Dysplasia: Reviewing the Evidence for Nonsurgical Management

Summary:

This systematic review of available evidence for nonsurgical management of hip dysplasia considered 14 articles and scored nonsurgical management including: activity restrictions, weight management, acupuncture, modulation of joint disease by polysulfated glycosaminoglycans, mesenchymal stem cell therapy, and extra corporeal shock wave therapy.

Conclusion:

“Weight management is an effective and important component of managing dogs with HD and associated osteoarthritis. Techniques that modulate the progression of joint disease may also be beneficial for treating dogs with HD. Further studies are needed to investigate other methods of managing HD such as hydrotherapy and physical rehabilitation.”

Author & Journal:Shaw, Kristin Kirkby et al, Veterinary Surgery, 2012

Comparative Efficacy of Water and Land Treadmill Training for Overweight or Obese Adults

Summary:

Comparative Efficacy of Water and Land Treadmill Training for Overweight or Obese Adults. {Humans}

Purpose: No known previous research has been published to explore the efficacy of underwater treadmill (UWTM) exercise training for the obese. Thus, the purpose of this study was to compare changes in physical fitness, body weight, and body composition in physically inactive, overweight, and obese adults after 12 wks of land treadmill (LTM) or UWTM training.

Conclusion:

UWTM and LTM training are equally capable of improving aerobic fitness and body composition in physically inactive overweight individuals, but UWTM training may induce increases in LBM.

Author & Journal:Greene, Nicholas, et al, Medicine & Science in Sports & Exercise, 2009

Integration of a physical training program in a weight loss plan for overweight pet dogs.

Summary:

To investigate whether a controlled physical training plan for overweight dogs during a weight loss program would improve cardiorespiratory fitness and better preserve lean body mass, compared with results for dogs undergoing a weight loss program based on caloric restriction alone.

Conclusion:

Conclusion:The controlled exercise plan used with a dietary weight loss program prevented loss of lean body mass in dogs. This finding supports inclusion of controlled physical training for obesity management in dogs.

Author & Journal:Vitger AD, et al. JAVMA 2016

Association among exercise duration, lameness severity, and hip joint range of motion in Labrador Retrievers with hip dysplasia.

Summary:

To evaluate factors associated with lameness severity and hip joint range of motion in dogs with hip dysplasia and to assess the association between hip joint range of motion and degree of lameness.

Conclusion:

Conclusion:Longer daily exercise duration was associated with lower lameness scores in dogs with hip dysplasia. Dogs with hip joint luxation secondary to hip dysplasia had higher lameness scores than did dogs without hip joint luxation.

Author & Journal:Greene LM, et al. JAVMA 2013.